Science Based

Science Based

At Nature Made®, scientific research is the starting point for every product we make. Whether from published research or our own clinical trials, we only make dietary supplements that our scientist’s have concluded science supports as being safe and providing a benefit to our consumers.  That means we consider the scientific basis for each product long before it is developed, manufactured, and put on the shelf.

We aim to be the model against which all other dietary supplement companies are measured, which is why we have a rigorous three-pronged approach to evaluate and substantiate the scientific basis for our products:

Review of Scientific Literature
We constantly track emerging science on nutrition, but we do not chase fads. On staff we have PhDs and Registered Dietitians that lead health and nutrition discussions within our company, and we also discuss the latest scientific facts with the Nature Made Scientific Advisory Board. Through this review process, we often choose not to develop products that may be popular or in the news because they lack sufficient benefit or safety evidence. Among examples, Nature Made long delayed developing a Cinnamon product and never followed the trend to develop an Ephedra product. Why?  Because we want to ensure that our products have scientific support for safety and consumer benefit.  Scientific support is not the same thing as scientific consensus; Pharmavite may act on credible emerging science before there is scientific consensus on the product.

Support for Public Studies
We feel strongly that vitamins and supplements deserve more independent academic and institutional research. We are proud that Nature Made supplements are sought out for clinical research studies by the leading science and health institutions because they can count on our product quality and consistency. In the last 20 years, Nature Made® products have been utilized or cited in numerous clinical studies.

Product-Specific Clinical Trials
For certain Nature Made products, we design and implement clinical studies to measure the benefit provided by our unique ingredients or blends. As a first example, we recently clinically tested our CholestOff™ product and, as we expected based on the studies previously done on the main ingredient in our product, found our product provided clear efficacy for lowering LDL cholesterol levels. We intend to continue this path of specific clinical studies for select Nature Made products.

Beyond our products, we are committed to advancing Evidenced-Based Nutrition (EBN) science – an inclusive research model that considers the totality of all available evidence. Our experts work closely with researchers and health care professionals to share information and engage in dialogue to better understand the human body and what makes people healthier.

Quality Control

Quality Control

For 40 years, we have been obsessed with quality at Nature Made®. From ingredient sourcing, to industry-leading manufacturing practices, to our third-party verification approach, we believe it is our responsibility to lead in delivering quality products and a quality consumer experience.

This commitment to quality is critical because each year Nature Made produces more than 150 kinds of supplements, filling 120 million bottles with 11.5 billion tablets, capsules, and softgels. It is a responsibility we embrace. We have often been part of pushing the supplement industry forward, and setting the standards that become the model for industry-wide regulation.

As part of a commitment to quality, Nature Made has a strict quality control process for responsible manufacturing. In addition, we invest millions of dollars in new technologies and follow rigorous production processes to ensure the superior quality we promise to our customers. This commitment to quality relies on three foundational elements:

Sourcing
The path to quality products at Nature Made starts well before reaching our manufacturing centers. We work with the highest quality suppliers, and we ensure the quality levels of each new supplier via audits conducted by ourselves or experts we select. This ensures that our suppliers have clean, compliant facilities that follow Good Manufacturing Practices (GMP). Throughout the sourcing process we require our suppliers to show a Certificate of Analysis (COA) for the identity and quality of the ingredients they provide us.

Our Process
From the moment ingredients reach our US-based manufacturing facilities, we are dedicated to some of the most demanding safety and quality standards in the industry. Every step of our product development process is focused on delivering the highest quality dietary supplements possible. When ingredients arrive, they are tested for identity, and we continue verification at every stage of the manufacturing process to ensure we meet or exceed industry standards -- using techniques like infrared scanning, high performance liquid chromatography and mass spectrophotometry. As ingredients are weighed, blended, compressed, encapsulated, inspected and finally packaged as different vitamin products, we test or inspect appropriately to ensure quality.

Independent Third-Party Verification
We are immensely proud of our quality, but you don’t need to take our word for it. Verification by knowledgeable, independent experts ensures that our commitment to quality is worthy of your trust. As a trailblazer in the supplement industry, Nature Made was the first vitamin brand to earn United States Pharmacopeia (USP) verification through the USP dietary supplement verification program on many of its products. As well, Nature Made is the #1 Pharmacist Recommended brand in six key segments as ranked by Pharmacy Times, which polls pharmacists across the country about the brands they recommend.

Studies Using Nature Made

Studies Using Nature Made

For 20 years, Nature Made® has been a brand of choice for academic and public research studies on dietary supplements due to the quality and consistency our products provide.

From a substantial total list, we are pleased to share links to a few of the most well-known studies that used Nature Made products:

• Determination of coenzyme Q10 content in raw materials and dietary supplements by high-performance liquid chromatography-UV: collaborative study. (Lunetta, Roman; 2008; Ten collaborating labs)
http://www.ncbi.nlm.nih.gov/pubmed/18727527
Key finding: HPLC-UV testing is effective and dependable for CoQ10

• Effects of short-term folic acid and/or riboflavin supplementation on serum folate and plasma total homocysteine concentrations in young Japanese male subjects. (Araki, et al. 2006; Japan Women’s University)
http://www.nature.com/ejcn/journal/v60/n5/abs/1602351a.html
Key finding: Serum folate concentrations increased in folic acid groups

• Premenopausal overweight women do not lose bone during moderate weight loss with adequate or higher calcium intake. (Riedt, et al; 2006; Rutgers University)
http://www.ncbi.nlm.nih.gov/pubmed/17413095
Key finding: Bone mass was maintained with calcium supplementation

• Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation. (Bruno, et al. 2005; Linus Pauling Institute at Oregon State University)
http://www.ncbi.nlm.nih.gov/pubmed/16458200
Key finding: Vitamin C recycles Vitamin E

• S-Adenosyl-L-Methionine (SAMe) as an Adjunct for Resistant Major Depressive Disorder: An Open Trial Following Partial or Nonresponse to Selective Serotonin Reuptake Inhibitors or Venlafaxine. (Alpert, et al. 2004)
http://www.ncbi.nlm.nih.gov/pubmed/15538131
Key finding: Potential of SAM-e as treatment approach (small sample size)

• Vitamin E treatment of nonalcoholic steatohepatitis (NASH) in children: A pilot study. (J. Lavine. 2000)
http://www.jpeds.com/article/S0022-3476(00)05040-X/abstract
Key finding: Vitamin E potential treatment for NASH

#1 Pharmacist Recommended

 #1 Pharmacist Recommended

Nature Made is again proud to earn a No. 1 ranking among pharmacists in 7 key segments according to the 2012 Pharmacy Times survey. We aim to be the model against which all other dietary supplement companies are measured and for over 40 years, we have been obsessed with quality. We believe it is our responsibility to lead in delivering quality products and a quality consumer experience. Everyday we make choices and take actions that ensure the scientific-basis and quality of Nature Made® vitamins and supplements.
We look forward to the release of rankings for 2013, where we will strive to be recognized again as the #1 Pharmacist recommended brand in key segments.

2006
2007
2008
2009
2010
2011
2012
Letter Vitamins




#1
#1
#1
- Vitamin A
#1
#1
#1
*
*
*

- Vitamin B
#1
#1
#1
#1
*
*
*

- Vitamin C
#1
#1
--
--
*
*
*

- Vitamin D
#1
#1
#1
#1
*
*
*

- Vitamin E
#1
#1
#1
#1
*
*
*









Flax Seed
#1
#1
#1
#1
#1
#1
#1
Omega 3 / Fish Oil
#1
#1
#1
#1
#1
#1
#1








CoQ10
#1
#1
#1
#1
#1
#1
#1








Herbal Supplements
#1
#1
#1

Diabetic Multivitamins






#1
Garlic Supplements






#1

* Letter Vitamin segment was first combined in 2012

The other categories ranked as part of the Vitamins and Supplements section were bone/joint strengtheners, cholesterol management, immune support, magnesium supplements, calcium supplements, fiber supplements, ocular nutritional supplements, diet aids, multivitamins, high-potency vitamin C supplements, iron supplements, probiotic dietary supplements, cranberry supplements, oral nail strengtheners, mood health supplements and nutritional supplements.


Contact Us

Email
Thank you for your interest in Nature Made Products. For a quick answer to many of your questions please visit our Product FAQ page.
If you don't find the answer to your question then please use this link to Contact Us or
Email :  naturemade.herbal@gmail.com

Phone
To contact our Consumer Affairs Department, Monday - Friday; 7 a.m. to 4 p.m.: 0857-31-10-2012

Contact Us
To contact our corporate office:
P.O. Box 9606
Mission Hills, CA 91346-9606